Functional Testing

Chemistry at Work™ • Private Screening

Different tests.
Different views into your biology.

From metabolic biomarkers to cellular response to comprehensive nutritional analysis, Chemistry at Work™ gives organizations different ways to bring private, personal laboratory information to employees.

Personal insight. Private results. A deeper view of individual biology.

Chemistry at Work screening options
AT-HOME COLLECTION Look at the
chemistry your
metabolism leaves behind.
At-Home Collection

Screening Option 1

Metabolic Nutritional Assessment

See what your metabolism can reveal.

This option measures metabolites associated with nutrient-related biochemical pathways, providing information for an individualized nutritional review.

Instead of asking only what nutrients are present, it examines the chemical footprints created as metabolism does its work, providing another view of an individual's nutritional picture.

Measurements and Areas of Interpretation

Nutritional Insights

Metabolic indicators associated with B1, B2, B3, B6, B7, B9 & B12

Antioxidant-related interpretation

Indirect mineral-related interpretation: magnesium, manganese, molybdenum & zinc

Amino acids

Laboratory nutritional interpretation for professional review

Metabolic Insights

Metabolites associated with energy pathways

Neurotransmitter-related metabolites

Oxidative-stress-related biomarkers

Digestive- and microbial-associated metabolites

Metabolites associated with methylation and glutathione pathways

Many nutrient interpretations are indirect, rather than measurements of vitamin or mineral concentrations. These findings do not, by themselves, establish a deficiency, brain neurotransmitter levels, or overall methylation or detoxification capacity. Interpretation considers health history, diet, medications and other findings; additional testing may be appropriate. Exact coverage depends on the ordered panel.

At-Home Collection Metabolic Biomarkers Nutritional Insight Biochemical Pathways

Testing availability: Metabolic Nutritional Assessment is unavailable in NY, NJ, and RI.

Optional Additional Assessments

Explore more of the nutritional picture.

Stress Response (Cortisol)
Sleep & Recovery

Available through separate assessments where offered; these are not measurements included in the core Metabolic Nutritional Assessment.

View assessment coverage

Specific measured metabolites and their associated functional nutrient indicators are shown below. Vitamin names describe pathways assessed indirectly; they are not direct measurements of vitamin blood concentrations.

Digestive and microbial metabolites

Indoleacetic acid, phenylacetic acid, dihydroxyphenylpropionic acid, 3-hydroxypropionic acid, 4-hydroxyphenylpyruvic acid, benzoic acid, hippuric acid, D-arabinitol, citramalic acid, tartaric acid.

Cellular energy and fatty-acid metabolism

Adipic acid, suberic acid, pyruvic acid, lactic acid, α-hydroxybutyric acid, β-hydroxybutyric acid, β-hydroxy-β-methylglutaric acid, citric acid, cis-aconitic acid, isocitric acid, α-ketoglutaric acid, succinic acid, malic acid.

Metabolic indicators associated with B-vitamin pathways

Vitamin B1 (thiamine), B2 (riboflavin), B3 (niacin) and alpha-lipoic-acid-related metabolism: branched-chain amino-acid catabolites including α-ketoadipic acid, α-ketoisovaleric acid, α-ketoisocaproic acid and α-keto-β-methylvaleric acid, plus glutaric acid and isovalerylglycine. Vitamin B6 (pyridoxine): xanthurenic acid and related kynurenine-pathway markers. Vitamin B7 (biotin): 3-hydroxyisovaleric acid and 3-hydroxypropionic acid. Vitamin B9 (folate): formiminoglutamic acid (FIGlu). Vitamin B12 (cobalamin): methylmalonic acid. These are functional indicators, not direct vitamin concentrations.

Neurotransmitter-related metabolites

These are measured metabolites, not direct measurements of neurotransmitter levels in the brain. Kynurenic acid, quinolinic acid, kynurenic/quinolinic ratio, xanthurenic acid, homovanillic acid, vanillylmandelic acid, 3-methyl-4-hydroxyphenylglycol, 5-hydroxyindoleacetic acid.

Oxidative-stress-related biomarkers, glutathione-pathway metabolites and oxalates

Pyroglutamic acid, α-ketophenylacetic acid, α-hydroxyisobutyric acid, orotic acid, glyceric acid, glycolic acid, oxalic acid, lipid peroxides, 8-hydroxy-2′-deoxyguanosine; urinary creatinine for concentration adjustment.

Essential and conditionally essential amino acids

Arginine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, taurine, threonine, tryptophan, valine.

Other amino acids and related metabolites

Alanine, asparagine, aspartic acid, cysteine, γ-aminobutyric acid (GABA), glutamic acid, glutamine, proline, tyrosine, α-aminoadipic acid, α-aminobutyric acid, β-aminoisobutyric acid, cystathionine, citrulline, ornithine, urea, glycine, serine, ethanolamine, phosphoethanolamine, phosphoserine, sarcosine, 1-methylhistidine, 3-methylhistidine, β-alanine.

Other nutrient-related interpretation

The laboratory may use metabolic and amino-acid patterns to generate nutritional interpretations involving antioxidants (including vitamins C and E, vitamin A/carotenoids, glutathione, lipoic acid and coenzyme Q10) and minerals (magnesium, manganese, molybdenum and zinc). These interpretations are indirect, are not confirmed deficiencies, and require professional review in context.

Specific markers and collection requirements are subject to the ordered panel. Fatty-acid profiling and expanded elemental testing are not assumed to be part of this standard assessment. Cortisol and sleep-related assessments, where offered, are separate add-ons.

Professional Blood Draw

Screening Option 2

Cellular Functional Assessment

Explore how your cells
respond in the laboratory.

This assessment examines immune-cell growth responses under controlled laboratory conditions with individual nutrients and related compounds.

This screening option evaluates laboratory cellular responses across a 55-item panel of nutrients and related compounds. Results provide additional information to discuss with an appropriate healthcare professional.

Measurements and Areas of Interpretation

Nutritional Insights

B vitamins: B1, B2, B3, B5, B6, B7, B9, B12

Vitamins A, C, D, E & K

Minerals & trace elements

Amino acids

Antioxidants & other nutrients

Cellular Responses

Cellular micronutrient responses

Immune-cell growth responses

Laboratory cellular redox responses*

Laboratory oxidative-stress responses*

Laboratory antioxidant responses*

Measures immune-cell responses in the laboratory, not blood nutrient concentrations. A laboratory response alone does not establish a whole-body nutrient deficiency or demonstrate that supplementation will improve health. *Redox and antioxidant-response assessments depend on the ordered package.

VitaminsMineralsAmino AcidsAdditional Nutrients
How it works

The laboratory measures how well immune cells reproduce under controlled conditions and whether individual nutrients improve that response.

55
Nutrients & Compounds
Evaluated

Your cells.
Laboratory responses.
Information to discuss.

Testing availability: Cellular Functional Assessment is unavailable for patients in HI, NJ, NY, and RI.

Optional Add-On

Antioxidant Function Assessment

An optional laboratory assessment examines cellular responses to an oxidative challenge and selected antioxidant compounds. It does not measure overall antioxidant protection throughout the body.

49 antioxidant nutrients
& enzymes evaluated
View assessment coverage

Functional cellular response to the following nutrients and related compounds, based on the published 55-item panel list.

Vitamins

Thiamine (B1), riboflavin (B2), biotin (B7), cobalamin (B12), folate (B9), nicotinamide (B3), pantothenic acid (B5), pyridoxine (B6), vitamins C, A, D, E (delta-tocotrienol), K1, K2-MK7 and K2-MK4.

Minerals and trace elements

Boron, calcium, chromium, copper, iodine, iron, lithium, magnesium, manganese, molybdenum, selenium, strontium, vanadium and zinc.

Amino acids

Arginine, asparagine, cysteine, glutamine, glycine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, serine, taurine, threonine, tryptophan, tyrosine and valine.

Other nutrients and compounds

Carnitine, choline, coenzyme Q10, docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), glutathione, inositol, lipoic acid and oleic acid (omega-9).

Antioxidant protection assessment (package dependent)

An additional cellular antioxidant-function assessment may examine laboratory cell responses to an oxidative challenge and selected antioxidant compounds, including: Açaí berry, andrographis, astaxanthin, astragalus, bilberry, boswellia, camu camu, chlorophyll, cinnamon, echinacea, elderberry, garlic, ginger, ginkgo biloba, goji berry, grape seed, green tea, lavender, lycopene, maitake mushroom, mangosteen, milk thistle, moringa, noni berry, piperine, pomegranate, pycnogenol, quercetin, resveratrol, rhodiola root, shiitake mushroom, sulforaphane, turmeric, wild cherry bark, zeaxanthin, beta-carotene, catalase, coenzyme Q10, glutathione, lipoic acid, lutein, melatonin, NADH, pyrroloquinoline quinone (PQQ), selenium, superoxide dismutase (SOD), vitamins C and E, and zinc.

The antioxidant component is not automatically included with every cellular assessment. This assay measures stimulated cellular functional responses, not the concentration of these substances in the bloodstream. Published component list dated July 2022; current ordering menu should be confirmed.

Blood & Urine Collection

Screening Option 3

Comprehensive Nutritional Assessment

A broader set of nutritional and metabolic biomarkers.

This laboratory-based assessment combines more than 125 blood and urine biomarkers to provide measured values and nutrient-related indicators for an individualized nutritional review.

Results bring together amino acids, fatty acids, nutrient elements and metabolites associated with energy metabolism, oxidative stress and methylation pathways. Indirect indicators do not, by themselves, establish a deficiency or measure overall mitochondrial or methylation function; findings require interpretation in context.

01Nutrient-Related Indicators
02Metabolic Biomarkers
03Fatty Acids & Amino Acids
04Oxidative-Stress Markers
COMPREHENSIVE NUTRITION 125+
Biomarkers.
Blood & urine assessment
View assessment coverage

Blood and urine biomarkers include the following measured metabolic markers and nutrient-related indicators. Vitamin names refer to functional interpretation unless a direct analyte is specifically identified.

Digestive and microbial metabolites

Indoleacetic acid, phenylacetic acid, dihydroxyphenylpropionic acid, 3-hydroxypropionic acid, 4-hydroxyphenylpyruvic acid, benzoic acid, hippuric acid, D-arabinitol, citramalic acid, tartaric acid.

Cellular energy and fatty-acid metabolism

Adipic acid, suberic acid, pyruvic acid, lactic acid, α-hydroxybutyric acid, β-hydroxybutyric acid, β-hydroxy-β-methylglutaric acid, citric acid, cis-aconitic acid, isocitric acid, α-ketoglutaric acid, succinic acid, malic acid.

Metabolic indicators associated with B-vitamin pathways

Vitamin B1 (thiamine), B2 (riboflavin), B3 (niacin) and alpha-lipoic-acid-related metabolism: branched-chain amino-acid catabolites including α-ketoadipic acid, α-ketoisovaleric acid, α-ketoisocaproic acid and α-keto-β-methylvaleric acid, plus glutaric acid and isovalerylglycine. Vitamin B6 (pyridoxine): xanthurenic acid and related kynurenine-pathway markers. Vitamin B7 (biotin): 3-hydroxyisovaleric acid and 3-hydroxypropionic acid. Vitamin B9 (folate): formiminoglutamic acid (FIGlu). Vitamin B12 (cobalamin): methylmalonic acid. These are functional indicators, not direct vitamin concentrations.

Neurotransmitter-related metabolites

These are measured metabolites, not direct measurements of neurotransmitter levels in the brain. Kynurenic acid, quinolinic acid, kynurenic/quinolinic ratio, xanthurenic acid, homovanillic acid, vanillylmandelic acid, 3-methyl-4-hydroxyphenylglycol, 5-hydroxyindoleacetic acid.

Oxidative-stress-related biomarkers, glutathione-pathway metabolites and oxalates

Pyroglutamic acid, α-ketophenylacetic acid, α-hydroxyisobutyric acid, orotic acid, glyceric acid, glycolic acid, oxalic acid, lipid peroxides, 8-hydroxy-2′-deoxyguanosine; urinary creatinine for concentration adjustment.

Essential and conditionally essential amino acids

Arginine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, taurine, threonine, tryptophan, valine.

Other amino acids and related metabolites

Alanine, asparagine, aspartic acid, cysteine, γ-aminobutyric acid (GABA), glutamic acid, glutamine, proline, tyrosine, α-aminoadipic acid, α-aminobutyric acid, β-aminoisobutyric acid, cystathionine, citrulline, ornithine, urea, glycine, serine, ethanolamine, phosphoethanolamine, phosphoserine, sarcosine, 1-methylhistidine, 3-methylhistidine, β-alanine.

Fatty acid profile

Omega-3: α-linolenic acid (ALA), EPA, DPA, DHA; omega-6: linoleic acid, γ-linolenic acid, dihomo-γ-linolenic acid, arachidonic acid, docosatetraenoic acid, eicosadienoic acid; omega-9: oleic acid, nervonic acid; omega-7: palmitoleic acid, vaccenic acid; saturated and trans fatty acids, omega-3 index and fatty-acid ratios.

Nutrient and toxic elements

Nutrient elements may include chromium, cobalt, copper, iron, lithium, manganese, molybdenum, selenium, strontium, vanadium, zinc, calcium, magnesium, potassium and sulfur. Toxic-element markers may include lead, mercury, arsenic and cadmium; expanded element coverage depends on the collection and panel.

Additional oxidative-stress markers

Glutathione, coenzyme Q10, lipid peroxides and 8-hydroxy-2′-deoxyguanosine, with availability dependent on the specimen and selected panel.

Vitamins addressed by functional interpretation

B1 (thiamine), B2 (riboflavin), B3 (niacin), B6 (pyridoxine), B7 (biotin), B9 (folate) and B12 (cobalamin) are evaluated through specific metabolic indicators, not direct vitamin-level assays. Vitamins A, C and E may appear in antioxidant-support recommendations rather than as directly measured concentrations. Vitamin D is a separate optional add-on, not a standard included measurement.

The full panel combines urine-based metabolic markers with blood-based components. Genetic variants and vitamin D may be available as separately ordered add-ons; they are not represented as standard included measurements. Exact coverage varies with the ordered version and collection method.

Four Screening Pathways

Different ways to explore personal chemistry.

Choose from four private screening approaches, each offering a different view of personal health and nutrition.

At-Home Testing

Screening Option 1

Metabolic Nutritional Assessment

Metabolic biomarkers and nutrient-related indicators for professional interpretation.

Blood-Based

Screening Option 2

Cellular Functional Assessment

Laboratory immune-cell responses to nutrients and related compounds.

Blood & Urine

Screening Option 3

Comprehensive Nutritional Assessment

Blood and urine measurements of nutrients, fatty acids and metabolites associated with biochemical pathways.

Biomarker Testing

Screening Option 4

Blood-Based Biomarker Testing

Laboratory biomarkers across metabolic, cardiovascular, thyroid, nutrient, and general wellness areas.

Compare Options

See the differences at a glance.

Compare collection approach, primary insight area, privacy, and follow-up options.

Screening Feature
Screening Option 1Metabolic Nutritional Assessment
Screening Option 2Cellular Functional Assessment
Screening Option 3Comprehensive Nutritional Assessment
Screening Option 4Blood-Based Biomarkers
Sample / Collection
At-home collection
Professional blood draw
Blood draw & urine sample
Blood collection
Primary Lens
Comprehensive nutritional insights
Laboratory cellular responses
125+ nutritional & metabolic biomarkers
Clinical biomarkers
Individual Results
✓Yes
✓Yes
✓Yes
✓Yes
Retesting
Available
Available
Available
Available
Screening Option 1Metabolic Nutritional Assessment
CollectionAt home
Primary LensComprehensive nutrition
Individual ResultsYes
RetestingAvailable
Screening Option 2Cellular Functional Assessment
CollectionProfessional blood draw
Primary LensLaboratory cellular responses
Individual ResultsYes
RetestingAvailable
Screening Option 3Comprehensive Nutritional Assessment
CollectionBlood draw & urine
Primary LensExpanded nutritional & metabolic biomarkers
Individual ResultsYes
RetestingAvailable
Screening Option 4Blood-Based Biomarkers
CollectionBlood collection
Primary LensClinical biomarkers
Individual ResultsYes
RetestingAvailable
After Screening

Help employees understand what comes next.

Screening can be paired with independent professional support so employees can better understand their results, identify appropriate follow-up, and decide what questions to bring to their own healthcare providers.

Dietitian Guidance

Participants book directly with a registered dietitian through the program portal, may choose to share their results, and use insurance where applicable or self-pay.

Follow-Up

Preliminary findings can be reviewed with an appropriate professional and, when needed, verified through additional testing before treatment decisions.

Retesting Options

Follow-up screening can be incorporated where appropriate to give employees another point of reference over time.

Individual screening results stay private.

Chemistry at Work™ is structured so employers can sponsor screening and education without receiving or managing an employee's individual screening results.

Private Results

Individual screening results are delivered to the participant through the appropriate testing or provider pathway.

No Employer Results Access

Employers do not receive an employee's individual laboratory or screening results through Chemistry at Work.

GHG Does Not Receive Individual Results

Good Health Geek coordinates program delivery and does not receive individual screening results. Results remain with participants and their testing providers.

Built for Employers

Simple for the employer. Private for the employee.

The selected screening pathway can be integrated into the Chemistry at Work™ rollout without requiring HR to handle individual screening information.

1

Choose the Screening Path

Select Screening Option 1, 2, 3, 4, or the approved combination that best fits the organization.

2

Employees Receive Access

Participants receive the appropriate ordering, collection, or kit instructions.

3

Private Testing

Samples are collected and processed through the selected testing provider.

4

Employee-Directed Next Steps

Employees receive their individual results through the applicable provider pathway and can access appropriate follow-up resources.

FAQ

Common Questions

Does every employee have to use the same testing option?

Screening pathways are chosen by the employer. All participating employees receive the same screening pathway.

Does Good Health Geek receive employee test results?

No. Individual results are delivered to participants through the applicable laboratory or provider pathway. Good Health Geek does not receive individual results.

Does the employer receive individual results?

No. Chemistry at Work™ is designed around employee privacy. Individual screening information is not provided to the employer.

Can employees be tested again later?

Retesting can be incorporated where appropriate. For example, an employer program may include a follow-up screening several months after the initial test.

Is professional support available?

Yes. Participants access registered dietitian networks through the program portal and book directly with a provider. Appointments are billed separately through insurance or self-pay. The provider confirms network participation and coverage before the visit. Participants may choose to share their testing results with their dietitian for individualized nutrition guidance.

Chemistry at Work™

Bring personal insight to your workforce.

Build a Chemistry at Work™ program around the screening approach that fits your organization.

Contact Good Health Geek →
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Proudly U.S.-Based. Good Health Geek and its laboratory testing and registered dietitian partners are based in the United States, supporting employers and employees nationwide.